Professor Sadreddin M. Ardehali

Dept. of Parasitology and Mycology,School of Medicine,

            Shiraz University of Medical Sciences

            Shiraz, P.O.Box 71345-1741 , I.R.Iran



Marital Status:   Married, two children

Educational Background:

     1.     Ph.D. in Microbiology and Immunoprotozoology, 1974, from London

                School of Hygiene and Tropical Medicine, London, England.

     2.     M.S. in Microbiology, 1971, from Shiraz University, Shiraz, Iran.

     3.     California Clinical Laboratory License and Certificate in Medical

                Technology, 1966, Mercy Hospital, San Diego, California, U.S.A.

     4.     B.S. in Microbiology, 1965, San Diego State College, San Diego,

                California, U.S.A.

Teaching Experience:

     1.     Assistant Professor Department of Microbiology, Medical School,

                Shiraz University, 1974-1978.

     2.     Associate Professor, Department of Microbiology, Medical School,

                Shiraz University, 1978-1991.

     3.     Professor, Department of Microbiology, Shiraz University of Medical

                Sciences 1991. Duties included teaching Medical Parasitology,

                part of Medical Microbiology to medical and paramedical students;

                taking part in teaching part of Immunology of infectious diseases

                to the graduate students (M.S. and Ph.D.), supervising graduate

                students in Microbiology and residents from veterinary school,

                Shiraz, Iran.


Research Experience:


     1.     Two years of research experience on acquired and innate immunity

                in experimental leishmaniasis, Department of Microbiolgy Medical

                School, Shiraz University, 1969-1971.


     2.     Three years of research experience at the Divistion of Immunology

                Kennedy Institute of Rheumatology, London, England and the

                Department of Medical Protozoology, London School of Hygiene and

                Tropical Medicine, London, England. The research was concerned

                with the studies on the effect of humoral factors on Leishmania

                organisms 1971-1974.


     3.     Eight years of research experience on immunology and

                immunodiagnosis of parasitic diseases prevalent in Iran

                (Toxoplasmosis, Leishmaniasis and Hydatid diseases). Department of

                Microbiology, Medical School, Shiraz University, 1974-1984.


     4.     One year of research experience on production and partial

                characterization of monoclonal antibodies against Leishmania

                organisms at the World Health Organization Immunology Research and

                Training Center, Lausanne, Switzerland, September 1984-August,1985.


     5.     In vitro studies on the phagocytic processes of immune complexes

                by SLE prone and non-prone murine macrophages, Department of

                Medical Pathology, Medical School, University of California, Davis,

                October, 1985-1986.


     6.     Immunology of leishmaniasis characterization of Leishmania

                organisms using isoenzyme and monoclonal antibodies 1986.



Clinical Laboratory Experience:


     1.     Medical Technologist, Mercy Hospital, San Diego, California,

                January 1966 - August 1966.


     2.     Supervision of diagnostic bacteriology laboratory, Isfahan Public

                Health Laboratory Center, January, 1967 - February, 1969.


     3.     Bacteriologist, bacteriology division, Reference Laboratory,

                Tehran, Iran, March 1969 - September, 1969.


     4.     Supervision of serodiagnosis of parasitic diseases laboratory,

                Department of Microbiology, Medical School, Shiraz University,

                Shiraz, Iran, 1975-1984.


     5.     Supervision of the clinical parasitology laboratory, Faghihi

                hospital Medical School, Shiraz University 1980-1984.


     6.     Supervision of Clinical Microbiology section Mirhosseini Hospital

                Shiraz, Iran, 1995-.





     1.     Recipient of a 3-year grant from the CENTO to study for Ph.D. at

                the London School of Hygiene and Tropical Medicine, London,

                England 1971-1974.


     2.     Recipient of WHO fellowship to attend the course on Immunology of

                infectious diseases, August 30 - September 27, 1978, Lausanne,



     3.     Sabbatical leave from Shiraz University of the WHO Immunology

                Research and Training Center, Lausanne, Switzerland September

                1984 - August, 1985.


     4.     Research Fellowship:  Department of Medical Patholgy, Medical

                School, University of California, Davis, California, October



     5.     WHO Training grant for isoenzyme characterization of Leishmania 3

                months 1990-1991 (London, England).


     6.     WHO Grant for characteriztion of Leishmania using monoclonal

                antibodies one week 1993 (Cali, Colombia).


     7.     Visiting Professor of Microbiology Hamad Medical Corporation

                Department of Laboratory Medicine and Pathololgy, May 19-26, 1990

                (Doha, Qatar).


Biography in:


     1)     Who is Who in the world the 14th edition 1997.


     2)     International Biographical Center Dictionary of International

                Biography 26th edition 1998.





     1.     Rezai, H., Haghighi, P. and Ardehali, S. (1972) Histological

                appearance of the site of innoculation and lymphnodes of guinea

                pig at various times after infection with L. enriettii.

                Transactions of the Royal Society of Hygiene and Tropical

                Medicine 66.225-234.


     2.     Ardehali, S. (1974) The effect of homologous and heterologous

                rabbit antisera on the growth of Leishmania enriettii and

                Leishmania tropica major and their differentiation by quantitative

                Adler test. Transaction of the Royal Society of Hygiene and

                Tropical Medicine 68, 266.


     3.     Rezai, H., Ardehali, S., and Gettner, S. (1975) Anti - Leishmania

                activity of normal animal sera. Annals of Tropical Medicine and

                Parasitology 69, 29 - 33.


     4.     Ardehali, S., Kohaneb, J., Gerami, S., Behforouz, N., Rezai, H.,

                and Vaez - zadeh, K. (1977) Evaluation of

                counterimmuoelectrophoresis, crosselectroimmuno diffusion and agar

                gel diffusions for immunodiagnosis of human hydatid disease.

                Transactions of the Royal Society of Tropical Medicine and

                Hygiene, 71,481 - 485.


     5.     Ardehali, S. and Khoubyar, K. (1978) Uptake of different Leishmania

                by mouse peritoneal exudate cells. Transaction of the Royal

                Society of tropical Medicine and Hygiene, 72, 645 - 646.


     6.     Rezai, H. R., ardehali, S., Amirhakimi, G. and Kharazmi, A.(1978)

                Immunological features of Kala - azar, American Journal of

                Tropical Medicine and Hygiene, 27, 1079 - 1083.


     7.     Sedaghat, A., Ardehali, S., Sadigh, M. and Buxton, M. (1978) The

                prevalence of Toxoplasma infection in Southern Iran. Journal of

                Tropical Medicine and Hygiene, October issue 204 - 207.


     8.     Ardehali, S., Khoubyar, K. and rezai, (1979) Effect of Cytochalasin

                B on Leishmania - macrophage interaction. Acta tropica, 36,15 - 22.


     9.     Ardehali, S., Sodeiphy, M., Haghighi, P., Rezai, H. and Vollum,D.

                (1980) Studies on chronic (lupoid) leishmaniasis. Annals of

                Tropical Medicine and Parasitololgy, 74, 1 - 7.



 10.     Rezai, H., Bahar, K., Behforouz, N., and Ardehali, S., (1980) An

                in vitro parasite macrophage macrophage interation and in vivo

                resistance of mice to Toxoplasma gondii. Acta Tropica, 37,21 29.


    11.     Kohaneb, J., Ardehali, S., and Rezai, H., (1980) Studies on

                antigenic relationship of Leishmania promastigotes by

                electroimmunodiffusion and crossed - electroimmunodiffusion.

                Transactions of the Royal Society of Hygiene and Tropical Medicine,



    12.     Azadeh, B and Ardehali, S., (1983) Malakoplakia of mastoid cavity,

                apcase report. Histopathology, 7, 129 - 134.


    13.     Kohanteb, D. J., Rezai, H. R. and Ardehali, S. M., (1984)

                Application of electroimmunodiffusion (EID) and crossed -

                electroimmunodiffusion (CEID) tests for the diagnosis of visceral

                leishmaniasis. Journal of tropical Medicine and Hygiene.

                87,201 - 205.


    14.     Azadeh, B., Samad, A and ardehali, S., (1985) Histological

                spectrum of cutaneous leishmaniasis due to Leishmania tropica.

                Transaction of the Royal Society of Hygiene and Tropical Medicine,

                79,631 - 636.


    15.     Kohanteb, D. J., Ardehali, S., and Rezai, H.R., (1987) Detection

                of Leishmania donovani soluble antigen and antibody in th urine of

                Kala - azar patients. Transactions of the Royal Society of

                Hygiene and Tropical Medicine 81,587 - 580.


    16.     Rezai, H. R. Ardehali, S., Fabbri, B and Teplitz, R. (1987) Effect

                of levamisole on binding of immune complex to mouse peritoneal

                Macrophages, Natural Immunity, 6, 167 - 170.


    17.     Rezai, H. R. Behbehani, A. Gettner, S. and S. Ardehali (1988)

                Effect of levamisole on the course of experimental leishmanisis

                in guinea pigs and mice. Hematological and Immunological findings.

                Annals of Troical Medicine and Parasitology, 82, 243 - 249.


    18.     H. Rezai, S. Ardehali and R. L. Teplitz (1989) Factors involved

                in Macrophage: Immune complex binding.Immunological Investigations,

                18(5), 671 - 688.


    19.     Rezai, H.R., S. Ardehali and R. Teplitz (1992) The effects of

                serum and some serum components on immune complex binding to

                macrophages. Medical Journal of the Islamic Republic of Iran.

                6 (3) 197 - 200.


    20.    Moaddeb, A S, Gettner, S., Ardehali, S. Studies on the causation

               agent of cutaneous Lieshmaniasis in Shiraz. Iran. Iranian Journal

               of Medica Sciences. 1993; 18: 28 - 33.


    21.    Edrissian, Gh. Ahanchin. A. R. Gharachahi, A. M. Ghorbani,

               M. Nadim, A. Ardehali, S. et al. Seraepidemiological studies of

               visceral leishmaniasis and search for animal resrvoirs in Fars

               province, southern Iran. Iranian Journal of Medical Sciences,

               1993; 18: 99 - 105.


    22.    Ardehali, S. Moein Rezakhanlou, A.R. Reticulocyte interference with

               lymphocyte separation in Blood of Patients with Kala - azar.

               Medical Journal of the Islamic Republic of Iran. 1993, 7:2.


    23.    Ardehali, S. Moein Rezakhankou, A.R., Sadeghi E. and S.Z. Tabei.

               Studies on T - Cell phenotypes in children with Kala-azar in Fars

               province, Iran, Medical Jouranl of the Islamic Requblic of Iran.

               1993; 7(3) 157 - 160.


    24.    Omrani, Gh. Farhadi, A. Parhizgar, A. Ardehali, S., M. Haghshenas,

               Visceral leishmaniasis as fever of undetermined origin. Medical

               Journal of the Islamic Republic of Iran.l994.


    25.    Ardehali, S., Sadeghi - Hassanabadi, A. Gharechahi, M. A., I.

               Ghahramani. Leishmania skin test in hyperendemic foci of zoonatic

               cutaneous leishmaniasis in Fars province Iran. Iranian Journal of

               medical Science. 1994, 19 - 21.


     26.   Ghaderi, A.A., Habibagahi, M., Amirghfran, Z.,Ardehali, S.: Determination of a

             shared epitope between cells from acute myeloblastic leukemia (AML) and acute

              lymphoblastic leukemia (ALL).  Med J Islamic Rep Iran, 1995; 9:253-255.


27.     Ardehali, S., Sadeghi - Hassanabadi, A. Moaddeb, A. Abdollahi, B., Malek        Hosseinik, Z., and D. Evans. Characterization of Leishmania isolated from cases with lymphadenopathy in Shiraz, Iran. Transactions of the Royal Society of Tropical Medicine and Hygiene . 1995, 89, 370-71

28.     Ardehali, S. Malaria vaccine immunology update. Proceedings of the 8th International Congress of Geographic Medicine. Edited by Ghaderi A.A. and N. Ghahremani, Shiraz University of Medical Sciences, May 7-May 10, 1995, Shiraz, Iran.

29.     Hatam, G.R. Hosseini, S.M.H. and Ardehali, S. Dermotropic isolates of Leishmania infantum from Iran. Transactions of the Royal Society of Hygiene and Tropical Medicine. 1997, 91, 440.

30.     Sadjjadi,S.M., Ardehali, S.M.,Shojaei,A.(1998) A case report of Linguatula serrata in throat of a woman in Shiraz, Iran. Med J Islam. Rep. Iran.12 (2) 193-194.

31.     Hatam.G.R.Hoseini,S.M.H and Ardehali,S. Evaluation of two biphasic culture media for isolation 0f Leishmania parasites from cutaneaous ulcers in Iranian patients. Medical Journal of Islamic Republic of Iran.1997.11(2) 178-179.

32.     Ardehali,S.Editorial:Leishmaniasis. Where do we stand? Iranian Journal of Medical Sciences.1996,21(3&4) 87-88.

33.     Sharifi,I.Ardehali,S.Motazedian,H. et al. Identification and characterization of Leishmania isolates in school children in Bam Southeastern Iran . Iranian Journal of Medical Sciences. 1997,22 (3&4)

34.     Edrissian,G.R. Nadim,A. Alborzi,A. and Ardehali,S. Visceral leishmaniasis; The Iranian Experience. Archives of Iranian Medicine, 1998, 1.1 .22-26

35.     Delir,S., Handjani,F.Emad,M. and Ardehali,S. Vulvar myiasis due to Wohlfahrtia magnifica. Clinical and Experimental Dermatology . 1999,24. 279-280

36.     Zerehsaz,F. Salmanpour,R.,Handjani,F.Ardehali, .al. Adouble blind randomized Clincal trial of a topical hebal extract(Z-HE)versus systemic meglumine antimoniate for the treatment of cutaneous leishmaniasis in Iran.International Journal of Dermatology.1999.38,610-612.

37.     Salmanpour,R. ,Handjani,F.,Zerehsaz,F.,Ardehali,S. and Panjehshahin,M.R. Erysiploid leishmaniasis: an unusual clinical presentation. European Journal of Dermatology.1999,9,458- 459.

38.     Ardehali,S.,Moattari,A.,Hatam,G.H.., Hosseini,SMH. And I.Sharifi. Characterization of Leishmania isolated in Iran: 1. Serotyping with species specific Monoclonal antibodies. Acta Tropica. 2000 ,75(3), 301-307.

39.     Aminlari , M., Ardehali, S., Tahernia, H. (2001) Detection of 63 kDa Protein in the Culture supernatant of Leishmania tropica and Leishmania major promastigotes, Iranian Journal of Medical Sciences 26 , 74-76.

40.     Motazedian , MH., Karamian, M., Noyes HA., Ardehali, S.,( 2002 ) DNA extraction and amplification of Leishmania from archived Giemsa stained slides for diagnosis of cutaneous leishmaniasis by PCR. Annals of Tropical Medicine and Parasitology; 96:31-34.

41.     Motazedian , MH. Noamanpour, B. Ardehali S.: Characterization of Leishmania parasites isolated from different provinces of Iran. Eastern Meditranean Journal ( Accepted for Publication ).


42.     Sadjjadi, S.M. Ardehali, S. Nomanpour, B., Kumar.V and  Izadpanah, A.    Diagnosisof cystic echinococcosis: Imaging or Countercurrent Immuno-electrophoresis? Eastersn Meditrranean Health Journal 2001, 7 (6) 907-911.

43.     Basiri, E., Ardehali, S., Kamali, E., Doroduchi, M., Habibaghahi, M., Sharifi, I and Ghaderi, A. 2002. Production and partial characterization of monoclonal antibodies to Leishmania. Iranian Journal of Medical Sciences; 27: 75-79.