Transplant Research Center
Address:
Namazi Hospital, Transplant Research Center
Tel: +98 711 6276211Fax: +98 711 6276211e-mail: transrsh@sums.ac.ir
Shiraz Transplant Research Center (STRC) began its activities in 2001 with the aim of research in different fields of transplantation, especially because:
· Shiraz University of Medical Sciences is one of the active centers of transplantation in kidney.
· Liver transplantation is exclusively done in Shiraz.
· There is an active team of bone marrow transplantation in hematology department.
· Corneal transplant is done in ophthalmology department.
Objectives STRC was developed to carry out the following goals:
§ Carry out research in different aspects of transplantation , to apply new tests for transplanted patients to create better life quality for them.
§ Gathering and registering exact and detail information about all of our transplanted patients, to have complete data from these patients such as viral markers and so on.
§ Training manpower for carrying out research and applying activities in the field of transplantation
Table 5-3: Academic Staff Strength
|
Research area |
Rank |
Academic Staff |
|
Pathology |
MD Professor |
S.Z. Tabei |
|
Surgery |
MD , Associate Professor |
S.A. Malekhosseini |
|
Pathology |
MD , Associate Professor |
B. Geramizadeh |
|
Hematology Department |
MD , Associate Professor |
M. Zakerinia |
|
Ophthalmology |
MD Assistant Professor |
H.R Jahadi Hosseini |
|
Physiology |
PhD Assistant Professor |
M. Varedi |
|
Pathology |
MD , Assistant Professor |
N.Azarpira |
|
Medical Genetics |
PhD , Student |
M.Ayatollahi |
|
Molecular Biology |
MS |
M.Aghdaei |
|
Virology |
PhD, Associate Professor |
A.Behzad-Behbahani |
|
Virology |
PhD , Assistant Professor |
R.Yaghoobi |
Current Research
§ Establishment of amniotic membrane tissue bank
§ Evaluation of amplified variable number of tandem repeats ( VNTR) in the detection of chimerism following bone marrow transplantion
§ Isolation , growth and function of neonatal and adult rat islet cells
§ Apoptosis and expression of Fas , Fas L , GMP 17 in cytotoxic T lymphocytes in renal transplant recipients and relation with acute rejection
§ Determination of humancytomegalovirus ( gN ) genotypes polymorphism in organ transplant patients
§ Construction of tissue-engineered heart valves
§ Autologous transplantation of tissue engineered urothelium into demucosalized ileal segments for experimental bladder wall reconstruction
§ Evaluation of the correlation between cystatin level & Cr,BUN & Apoptotic markers : GMP – 17 , fas , fas ligand , CD8+ T cells
§ Evaluation of the value of serum cystatin C as a surrogate marker for creatinine in liver & renal transplant patients
§ Effects of quercetin on the expression and adhesion of a2 B1 – integrin in kidney fibroblast from cyclosporine A-induced nephrotoxicity in rats
§ The effect of cytokine gene Polymorphism INFδ , TNFα , IL10 in acute rejection following renal transplantation
§ Therapeutic use of human adult bone marrow stem cell for neurigical disorders such as multiple sclerosis
§ Evaluation of effects of heparanase administration on skin autograft and allograft healin in rat
§ Comparison between IHC findings of HBSAg and HBCAg with grade and stage in HBV
§ Correlation of the hum oral immunologic factors with infectious complication after organ transplantation
§ Evaluation of the role of HBV virus genotype on inflammation , fibrosis and surface and core antigen level in liver biopsies of hepatitis B patients
§ Establishment of transplant sample bank
§ The effect of IL-10 promoter gene polymorphism with an occurrence of graft versus host disease in bone marrow transplant patients in Nemazi hospital
§ Isolation , characterization and deposition of human endothelial cells
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